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Leukoencephalomalacia Equine

Leukoencephalomalacia Equine
Equine leukoencephalomalacia (LEME), a non-infectious and highly fatal degenerative disease caused by the fungus Fusarium moniliforme, which releases mycotoxin in corn, feed or hay with inadequate handling and storage, when ingested causes intoxication affecting the central nervous system of equidae and causing a metabolic alteration that promotes softening of the white matter of the brain and liquefaction, which is nothing more than the transition from the solid state to the liquid state; Presenting sudden neurological signs, evolving to death in 72 hours. More attention should be paid to falling temperatures because they promote a thermal shock, favoring the development of the fungus. In addition to causing encephalomalacia, this fungus is also responsible for other diseases such as pulmonary edema, cancer, among.

Etiology
The leukoencephalomalacia pathology is caused by the mycotoxins released by the fungus Fusarium moniliforme.

Clinical Signs
Clinical signs presented by animals that consumed food contaminated with mycotoxins of the fungus Fusarium moniliforme, are related to the amount of toxin ingested, quality of their immunity and tolerance to this mycotoxin. Symptoms may take hours or days to appear after the ingestion of toxins; The initial clinical signs are hyperextubation, anorexia, chewing difficulty and food seizure, motor incoordination, head pressing, liver injury, blindness and depression; Already in an advanced state of the disease the animal presents lateral decubitus with movements of "pedalar", coma and death in up to 72

Prevention and Control
The best way to prevent and control this disease is to offer good quality ration, hay and / or silage, in addition to storing in ideal locations, with no sudden changes in temperature, low humidity (less than 15%) and airy location, thus providing a little place favored for the fungus. In the case of mold in the feed, hay or silage must be discarded the whole, whether the feed bag, bale of hay or silage since even removing the cake visible to the naked eye are mycotoxin that we can not see, it happens with This is why most of the food supplied contains toxins, even without mold, because of this, it is very important to use a toxin adsorbent to prevent your animal from becoming intoxicated. cumulative in the body.

Diagnosis
Diagnosis is made through clinical status, history, management and laboratorial examination (hemogram and biochemical), analysis of the food provided to the animal and if the animal dies examinations that detect changes of the central nervous system. However, there is no specific diagnosis for leukoencephalomalacia, since the clinical signs are similar to other pathologies such as tetanus, cerebral nematodes and others.

Treatment
There is no specific treatment for leukoencephalomalacia, but a support treatment should be made for the animal in order to try to reduce the damage caused in the central nervous system and the suffering since in more advanced cases the equidae can not stand.
Thinking about the health of your animal Univitta has developed a product called MOS, a broad spectrum adsorbent, ie adsorb many types of mycotoxins, not allowing the animal to absorb them, thus preventing intoxication or even equine leukoencephalomalacia.

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Postado Por: Gabriel Fernandes

Gabriel Fernandes
Veterinary medicine student, horse lover and currently works in the marketing and customer relationship department at Univittá Saúde Animal.

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